History and Usage:

Cox2Tame™ is a synergetic conflation of herbal extracts and oleoresins, full-spectrum herbal extracts recognized to furnish natural Cox-2 (cyclooxygenase-2) enzyme suppression. COX-2 suppression is crucial for the normal function of the joints, standard cellular healthy aging. Overexpression of COX-2 causes abnormal cell development. Cox2Tame™ contains Omega 3 fatty acids that are known to yield prostaglandins series 3 (PGE3) and suppress COX-2. GLA, extracted from Borage seed oil, increases the synthesis of prostaglandins series E1 (PGE1). Devil’s Claw utilizes COX-2 inhibitors known as iridoid glycosides, e.g., harpagosides. In clinical trials, iridoid glycosides were shown to improve joint movement and flexibility. White Willow Bark, containing the ingredients of aspirin, is a bitter herb and is an excellent source of flavonoids and salicylic derivatives (salicin and salicortin) responsible for inhibiting COX-2. Other Cox2Tame™ Herbs: Curcumin, Ginger, Quercetin, Resveratrol, and Green Tea. These are sources of potent phenolic antioxidants which break up the signaling actions that trigger COX-2 gene expression.

Label Information and Ingredients: Suggested Use: Take 1 to 3 softgels per day with water or juice, with meals, or as directed by your qualified health care consultant. DO NOT use if under the age of 18, pregnant, lactating, trying to conceive, or if using any medication.

Supplemental Facts Serving Size: 1 Softgel(s) Ingredients Per Serving % DV Fish Oil (Source of Omega 3 Fatty Acids) (Providing 122 mg EPA and 7 mg DHA) 290 mg * Gamma Linoleic Acid (GLA) (from Borage Oil) 50 mg * Resveratrol (Polygonum cuspidatum) (Derived from 200 mg Polygonum 8% extract) 16 mg * Curcumin (Curcuma longa) (95% Curcuminoids) (root) 300 mg * (Zingiber officinale) (rhizome) (15% Gingerols and Shogaols) 250 mg * Green Tea (Camellia sinensis) (45% polyphenols) 150 mg * Devil's Claw (Harpagophytum procumbens) (5% iridoid glycosides) (root) 250 mg * Quercetin 250 mg * White Willow Bark (Salicis cortex) (15% salicin) 200 mg * * Daily Value Not Established Notes: COX2TAME™ is a synergistic blend of herbal extracts and oleoresins (full spectrum herbal extracts) known to provide natural CycloOxygenase-2 (COX-2) enzyme inhibition.* COX-2 inhibition is important for healthy joint function, normal cellular development (overexpression of COX-2 causes abnormal cell development) and healthy aging.* COX2TAME™ contains Omega 3 fatty acids known to generate prostaglandins series 3 (PGE3) and inhibit COX-2.* GLA from Borage seed oil extract, enhances synthesis of prostaglandins series E1 (PGE1).* Devil's Claw contains COX-2 inhibitors iridoid glycosides, such as harpagosides, clinically proven to improve joint motility and flexibility.* White Willow Bark is a bitter herb rich in flavonoids and salicylic acid derivatives (salicin and salicortin) responsible for inhibiting COX-2.* Other COX2TAME™ Herbs/phytochemicals: Curcumin, Ginger, Quercetin, Resveratrol, Green Tea: sources of powerful phenolic antioxidants that disrupt the signaling processes that activate COX-2 gene expression.* Other Ingredients: Soybean oil, beeswax, carob extract and lecithin. Softgel consists of gelatin, glycerin and water. Soy and fish. No wheat, no gluten, no dairy, no egg, no shellfish, no nuts/tree nuts.

Caution: Keep out of the reach of children.

QUALITY AND POTENCY GUARANTEED Websites for Further Research:

http://www.arthritis.org/

http://www.cdc.gov/arthritis/

http://www.webmd.com/diseases_and_conditions/...

http://www.mayoclinic.com/health/arthritis/AR99999