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Jarrow Formulas

  • Promotes joint health.
  • Benefits brain activity.
  • Sustains liver function.

Jarrow Formulas SAM-e is a natural by-product of microbiological fermentation and is processed without the use of solvents in order to preserve 68-80% of SAM-e, which is the highest avail able active level. SAM-e is derived from amino acids and has been scientifically demonstrated to stimulate healthy joint, brain, and liver functions.

SAM-e has also been described as an activated form of the essential amino acid methionine, due to its formation through a combination of ATP with methionine. SAM-e is found in every living cell.

SAM-e has been tested by scientists in dozens of trials testing thousands of patients. The results have demonstrated that the beneficial effects of SAM-e include joint strength and generation of healthy connective tissue through transulfuration. In the transulfuration process, vital connective tissue components, including the chondroitin sulfates and glucosamine, are sulfated by SAM-e metabolites.

Suggested Use: Take 1 to 2 tablets per day on an empty stomach, or as directed by your qualified health care consultant.

Supplemental Facts
Serving Size: 1 Enteric-coated Tablet(s)

IngredientsPer Serving% DV
S-Adenosyl Methionine (from 400 mg of SAM-e tosylate disulfate) 200 mg *
* Daily Value Not Established

Notes: Jarrow FORMULAS® SAM-e 200 is foil blister-packed to maximize stability and safety. Do not use if outer seal of blister pack is broken. Full Potency 200 mg elemental SAM-e is derived from 400 mg of tosylate disulfate SAM-e. Store in a cool, dry place. Jarrow FORMULAS® SAM-e 200 pharmaceutical grade, stabilized SAM-e provides a full 200 mg elemental SAM-e from 400 mg of SAM-e tosylate disulfate. SAM-e 200 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product. Contains More of the Active S,S Form SAM-e (S-Adenosylmethionine) is a chiral molecule and therefore consists of two forms: (S,S) SAM-e and (R,S) SAM-e. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive. Jarrow FORMULAS' SAM-e is made naturally by microbiological fermentation and then specially processed without solvents to preserve 68-80% (S,S) SAM-e, the highest active level available. SAM-e is an amino acid derivative that has been clinically proven to benefit brain, joint and liver function.* Found in all living cells, SAM-e is often referred to as “activated” methionine (an essential amino acid) since it is formed by the combining of ATP with methionine. SAM-e has undergone dozens of trials involving thousands of patients. Researchers studying the beneficial effects of SAM-e have identified the following benefits of SAM-e: Joint Strength SAM-e supports the production of healthy connective tissue through transulfuration. In this process, critical components of connective tissue, including glucosamine and the chondroitin sulfates, are sulfated by SAM-e metabolites.* Brain Metabolism SAM-e methylation reactions are involved in the synthesis of neurotransmitters such as L-dopa, dopamine and related hormones, serotonin, epinephrine and phosphatidylcholine (a component of lecithin).* Longevity Methylation of DNA appears to be important in the suppression of errors in DNA replication. Demethylation of DNA is considered a contributor to the aging process. Proper methylation through substances such as SAM-e positively influences longevity.* Liver SAM-e metabolism supports the synthesis of glutathione (GSH) and glutathione -dependent enzymes (glutathione peroxidase and glutathione-S-transferase), which are substances important for liver function.*

Other Ingredients: Microcrystallinee cellulose, mannitol, sodium starch glycolate, silicon dioxide, glycerol behenate, magnesium stearate (vegetable source), enteric coating (methacrylate copolymers), titanium dioxide, magnesium silicate, triethylcitrate, riboflavin, glycerol palmitostearate, and medium chain triglycerides. Suitable for vegetarians/vegans. No wheat, no gluten, no soy, no dairy, no egg, no fish/shellfish, no nuts/tree nuts.

Caution: Individuals using prescribed medications such as antidepressants, including Selective Serotonin Re-Uptake Inhibitors (SSRIs) and MAO Inhibitors should consult a physician before using. Individuals with Parkinsons disease, bi-polar disorder or manic depression should not use SAM-e. Keep out of the reach of children.


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